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Sign up for our Health Tip of the Day newsletter, and receive daily tips that will help you live your healthiest life. Domestically produced CBD oil tends to be safer because of better growing and refining practices. To use CBD oil, place one or more drops under the tongue and hold the dose there for 30 to 60 seconds without swallowing. Capsules and gummies are easier to dose, although they tend to be more costly. The tricky part, of course, is calculating the exact amount of CBD per milliliter of oil.